Saturday played in 14 games for the Packers this season before being replaced late in the year by Evan Dietrich-Smith.
Sunday's Pro Bowl will be the last game of Saturday's career.
"We'll finish it with sunsets in Hawaii and call it a much better career than I would have anticipated," Saturday said.
Saturday, who entered the league as a non-drafted free agent, played for the Colts from 1999-2011 before joining Green Bay. In addition to making six Pro Bowls, Saturday was a first-team All-Pro twice and second-team All-Pro two times.