After weeks of speculation, Major League Baseball has handed down suspensions to the Biogenesis-linked players.
Of the 13 individuals disciplined, Yankees third baseman Alex Rodriguez was the only one to appeal, meaning he'll be expected to make his season debut when New York opens a three-game set against the White Sox in Chicago Monday night.
Rodriguez, the highest-profile player connected to the now-closed anti-aging clinic in Florida accused of supplying performance-enhancing substances, had the harshest penalty levied against him in the form of a suspension through the end of the 2014 season.
By appealing under the MLB drug policy, the 38-year-old Yankees star is eligible to play until such an appeal is heard by arbitrator Fredric Horowitz in the next three weeks.
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Rodriguez, who previously admitted to using steroids during a two-year period from 2001-03 while with the Texas Rangers, has yet to play in the majors this year as he recovered from offseason hip surgery and more recently, a quad injury.
Rangers slugger Nelson Cruz, Detroit Tigers shortstop Jhonny Peralta, San Diego Padres shortstop Everth Cabrera and pitcher Fautino De Los Santos, Yankees catcher Francisco Cervelli and outfielder Fernando Martinez, Philadelphia Phillies reliever Antonio Bastardo, Seattle Mariners catcher Jesus Montero, Houston Astros pitcher Sergio Escalona, New York Mets utility man Jordany Valdespin and outfielder Cesar Puello and free-agent pitcher Jordan Norberto each accepted 50-game bans as part of MLB's drug investigation.
Losing Cruz is a significant blow to the Rangers. The right fielder was pacing the club in homers (27) and RBI (76).
The Tigers braced for a lengthy suspension involving Peralta by acquiring Jose Iglesias from the Boston Red Sox last week.
Milwaukee Brewers outfielder Ryan Braun, the 2011 NL MVP, accepted a 65-game suspension last month for his role with the clinic.