MLB Home Run Predictions Today: HR Prop Bets for Friday, May 15
It's "Friday Fly Ball Frenzy," and this slate has plenty of pitchers bringing dangerous fly-ball profiles into matchups against hitters who can absolutely punish mistakes. The power spots are there, the splits line up, and several bats are in perfect positions to leave the yard Friday night.
We have Gunnar Henderson in a bounce-back spot against a pitcher getting crushed by lefties, Mickey Moniak bringing a hot bat into Coors Field against a righty struggling badly with left-handed power, and Brady House as a sneaky long-shot play against a fly-ball-heavy arm on the road. If you're chasing HR props Friday night, these are bats with serious moonshot potential.
All odds are from DraftKings Sportsbook and are subject to change. DraftKings does not sponsor this content.
Best Home Run Props Today
Gunnar Henderson Home Run Bet (+414)
Henderson feels like a great bounce-back home run target Friday after going hitless in the Yankees series. Now he gets Zack Littell, who has been serving up fly balls all season long. Henderson has already homered twice off Littell in his career, and most of his power this season has come against right-handed pitching. Littell has also been crushed by lefties, allowing 11 of his 14 home runs to them. This feels like the perfect spot for Gunnar to snap out of the slump with one big swing.
Mickey Moniak Home Run Bet (+286)
Moniak has been raking this season, and getting a Friday night game at Coors Field against Merrill Kelly feels like a pretty good recipe for another home run. Moniak already has 12 bombs this year, with nine coming at home, and he's been crushing right-handed pitching all season. Kelly has also had major problems with lefties, who are hitting .345 against him with most of the home runs he's allowed. Toss in the Coors Field boost, and this feels like a great spot for Moniak to go deep again.
Brady House Home Run Bet (+564)
House feels like a fun sneaky HR play Friday against Shane Baz. Everyone will be looking at James Wood in the Nationals lineup, but House has a pretty nice setup here too. Five of his six HRs have come against right-handed pitching, and he's been much better at home. Baz has also turned into a fly-ball machine this Monday and has struggled badly on the road. If House gets one elevated Friday night, this could cash at a pretty nice number.
2026 MLB HR Leaders
- DH Kyle Schwarber, Philadelphia Phillies (18)
- OF Aaron Judge, New York Yankees (16)
- OF Byron Buxton, Minnesota Twins (15)
- 1B Munetaka Murakami, Chicago White Sox (15)
- 1B Matt Olson, Atlanta Braves (14)
- DH Yordan Alvarez, Houston Astros (14)
- 1B Ben Rice, New York Yankees (13)
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This story was originally published May 15, 2026 at 4:30 AM.