July 3: Mary Elizabeth Anania is born in Jacksonville, Fla., to Elizabeth and Vincent Anania.
May: Elizabeth Anania graduates from UNC Law School, where she met John Edwards.
July 30: Elizabeth Anania marries John Edwards.
Elizabeth Edwards begins working as an associate at Harwell Barr Martin & Sloan, a law firm in Nashville, Tenn.
July 18: The couple's first child, Lucius Wade, is born.
John and Elizabeth Edwards move their family back to Raleigh, where she begins working in the North Carolina Attorney General's office; she later works as a bankruptcy lawyer at Merriman, Nicholls, and Crampton.
March 4: The couple's second child, Catharine Elizabeth ("Cate"), is born.
April 4: Wade Edwards is killed in a freak automobile accident on Interstate 40. Elizabeth Edwards retires from her legal practice and becomes administrator of the Wade Edwards Foundation.
April 24: At age 48, Elizabeth Edwards gives birth to a daughter, Emma Claire.
Nov. 3: John Edwards is elected to his first political office as a Democratic U.S. senator from North Carolina. The family soon moves to Washington, D.C.
May 19: Now 50 years old, Elizabeth Edwards gives birth to a son, John Atticus ("Jack").
Sept. 16: John Edwards announces his run for the presidency.
March 3: John Edwards withdraws from the presidential race.
July 6: Democratic presidential nominee John Kerry announces that John Edwards will be his running mate.
Nov. 2: President Bush and Vice President Cheney are re-elected, defeating Kerry and Edwards.
Nov. 3: John and Elizabeth Edwards get confirmation that she has cancer.
May: John Edwards says he will not run for president again if his wife's health worsens.
Summer: The family moves into a new 28,000-square-foot home on 100 acres outside Chapel Hill.
September: Elizabeth Edwards releases a book, "Saving Graces: Finding Solace and Strength from Friends and Strangers."
Dec. 28: John Edwards announces his intention to run for president in 2008.
March 22: John and Elizabeth Edwards announce that her breast cancer has returned. This time, the cancer is in her rib and is incurable. They plan to continue with the presidential campaign.
Jan. 30: Amid rumors of an extramarital affair, John Edwards suspends his campaign for the presidency.
Aug. 8: John Edwards admits to an affair with campaign videographer Rielle Hunter. Elizabeth Edwards admits she helped keep her husband's affair quiet.
May: Elizabeth Edwards' second book, "Resilience: Reflections on the Burdens and Gifts of Facing Life's Adversities," is published.
May: Elizabeth Edwards is interviewed on The Oprah Winfrey Show about her husband's affair and her new book.
August: Elizabeth Edwards opens Red Window, a furniture store in Chapel Hill.
Jan. 21: John Edwards admits publicly that he is the father of Rielle Hunter's baby. He and Elizabeth officially separate.
June 29: An updated version of "Resilience" is released. The paperback version adds a chapter on the breakup. Several interviews follow, including the "Today" show and "Larry King Live."
June: Elizabeth Edwards announces plans to sell the Chapel Hill house.
Sept. 17: Elizabeth Edwards appears on "The Nate Berkus Show" during the syndicated program's premiere week.
Dec. 7: Elizabeth Edwards dies at her home.